Endometriosis Institute

The cause of endometriosis remains unknown and because of this, there is no treatment available that will cure this disease. Over the years, the pharmaceutical industry has developed a variety of compounds in an attempt to control the disease and its symptoms. The Endometriosis Institute has participated in numerous clinical trials with these drugs. In the 1960s and 1970s, we evaluated danazol, the 1st effective medical treatment for endometriosis. In the 1980s and 1990s, we participated in clinical trials using different GnRH agonists. From the beginning of 2000, we studied different GnRH antagonists. Currently we are participating in clinical trials with compounds that selectively block estradiol beta receptor. We anticipate that in the near future we will be studying the effectiveness of drugs that selectively inhibit inflammatory cytokines.

Current Clinical Trials

A clinical research trial testing a nerve block to treat pelvic pain due to Endometriosis
A clinical research trial using a newly developed medication for the management of moderate to severe pelvic pain related to Endometriosis
A clinical research trial using a nerve block to treat the symptoms of Post Partum Depression (PPD)

Clinical

Since 2004, our IVF pregnancy rates in women with endometriosis younger than 35 are upwards of 50%. We also have had pregnancies and babies delivered from unfertilized cryo-preserved eggs. This offers women with endometriosis a chance for cryopreservation and storage of their eggs until they are ready to start a family.

Why Egg Freezing is Beneficial

Women with rapidly progressing endometriosis who are not in position to begin their families may benefit from cryopreservation of eggs for future fertilization and pregnancy.

Many women have unfertilized eggs cryopreserved and stored with a modified technique. The eggs were then thawed and fertilized and the resulting embryos were transferred.

This approach offers women with endometriosis, career women who wish to delay childbirth, couples troubled by freezing embryos, and for those facing treatments that will affect their fertility a chance for cryopreservation and storage of their eggs until they are ready to start a family.

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Please note: some images are of models, not actual patients.
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